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ABC294640 decreases [3H]S1P formation in a dose-dependent fashion with an IC50 value of 26 μM
SP-600125 is a specific JNK inhibitor
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with substantial reductions in plasma HCV RNA in patients chronically infected with genotype 1 HCV
Nutlin-3b Size:Solid 2 mg ABC294640 decreases [3H]S1P formation inNutlin 3a, also known as SML 0580, is an inhibitor of MDM2 (human homolog of murine double minute 2), which disrupts its interaction with p53, leading to the stabilization and activation of p53. Nutlin 3a activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression of MDM2 protein. Product information CAS Number: 675576 97 3 Molecular Weight: 581. 49 Formula: C30H30Cl2N4O4 Synonym: Nutlin 3b
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